Drug Information

Drug General Information
Drug ID
D0J9MP
Former ID
DNC006790
Drug Name
N-(3-(3-aminopropyl)phenyl)benzenesulfonamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528373]
Structure
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2D MOL

3D MOL
Formula
C15H18N2O2S
Canonical SMILES
C1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)CCCN
InChI
1S/C15H18N2O2S/c16-11-5-7-13-6-4-8-14(12-13)17-20(18,19)15-9-2-1-3-10-15/h1-4,6,8-10,12,17H,5,7,11,16H2
InChIKey
GTXNQXVWASTZFN-UHFFFAOYSA-N
PubChem Compound ID
11849197
Target and Pathway
Target(s) 5-hydroxytryptamine 6 receptor Target Info Inhibitor [528373]
KEGG Pathway Calcium signaling pathway
cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 528373J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.
Ref 528373J Med Chem. 2006 Aug 24;49(17):5217-25.Binding of sulfonyl-containing arylalkylamines at human 5-HT6 serotonin receptors.

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