Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0K0KH
|
||||
| Former ID |
DAP001534
|
||||
| Drug Name |
Tropisetron
|
||||
| Synonyms |
Navoban; Novaban; TKT; ICS-205930; Navoban (TN); Tropisetron (INN); [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] 1H-indole-3-carboxylate; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 1H-indole-3-carboxylate
|
||||
| Drug Type |
Small molecular drug
|
||||
| Company |
Novartis International AG
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C17H20N2O2
|
||||
| InChI |
InChI=1S/C17H20N2O2/c1-19-11-6-7-12(19)9-13(8-11)21-17(20)15-10-18-16-5-3-2-4-14(15)16/h2-5,10-13,18H,6-9H2,1H3/t11-,12+,13+
|
||||
| InChIKey |
ZNRGQMMCGHDTEI-ITGUQSILSA-N
|
||||
| CAS Number |
CAS 89565-68-4
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID |
586259, 7849191, 7980847, 9268089, 11111839, 12013648, 15222410, 26755041, 32961435, 34873056, 47805530, 48404460, 57288867, 57408379, 78731080, 85176985, 92309072, 104003611, 104234183, 113528005, 124881513, 135651284, 136037819, 136212975, 137248058, 140119381, 140836794, 142488962, 144203823, 152109096, 162177588, 163621151, 163686496, 163719193, 170466432, 176484497, 179316852, 184545081, 184654810, 184812293, 198945704, 223441795, 226408320, 226408321, 226408322, 229923840, 238285228, 242115154, 245129894, 245216191
|
||||
| SuperDrug ATC ID |
A04AA03
|
||||
| SuperDrug CAS ID |
cas=089565684
|
||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine receptor 3A | Target Info | Antagonist | [536647] | |
| KEGG Pathway | Serotonergic synapse | ||||
| NetPath Pathway | IL2 Signaling Pathway | ||||
| PANTHER Pathway | 5HT3 type receptor mediated signaling pathway | ||||
| Reactome | Ligand-gated ion channel transport | ||||
| WikiPathways | SIDS Susceptibility Pathways | ||||
| Iron uptake and transport | |||||
| References | |||||
| Ref 536647 | Emerging therapies for fibromyalgia. Expert Opin Emerg Drugs. 2008 Mar;13(1):53-62. | ||||
| Ref 539678 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 260). | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.