Drug General Information
Drug ID	D0K2HA
Former ID	DIB004789
Drug Name	PF-2413873
Synonyms	PF-02413873
Drug Type	Small molecular drug
Indication	Endometriosis [ICD9: 617; ICD10:N80]		Phase 1	[522505]
Company	Pfizer Inc
Structure		Download 2D MOL 3D MOL
Formula	C18H21N3O3S
Canonical SMILES	C(#N)c1c(cc(cc1C)Oc1c(nn(c1C)CS(=O)(=O)C)C1CC1)C
PubChem Compound ID	16662425
Target and Pathway
Target(s)	Progesterone receptor	Target Info	Antagonist	[550034]
KEGG Pathway	Oocyte meiosis
	Progesterone-mediated oocyte maturation
Pathway Interaction Database	Cellular roles of Anthrax toxin
Reactome	Nuclear signaling by ERBB4
	Nuclear Receptor transcription pathway
WikiPathways	Ovarian Infertility Genes
	Signaling by ERBB4
	Nuclear Receptors
References
Ref 522505	ClinicalTrials.gov (NCT00800618) A Study To Investigate How The Body Handles Multiple Doses Of PF-0243873 And To Investigate The Effect Of PF-02413873 On Sex Hormone Levels In Healthy Young Women. U.S. National Institutes of Health.
Ref 550034	Unusual base-catalyzed exchange in the synthesis of deuterated PF-2413873. Journal of Labelled Compounds. 08/2009; 52(10):435 - 442.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.