Drug Information

Drug General Information
Drug ID
D0K4CQ
Former ID
DAP000503
Drug Name
Indecainide
Synonyms
Indecainida; Indecainidum; Ricainid; Ricainide; Indecainida [Spanish]; Indecainide [INN]; Indecainidum [Latin]; Decabid (TN); LY-135837; 9-(3-((1-methylethyl)amino)propyl)-9H-fluorene-9-carboxamide; 9-(3-(Isopropylamino)propyl))fluorene-9-carboxamide; 9-(3-(Isopropylamino)propyl)-9-fluorenylcarboxamid; 9-[3-(propan-2-ylamino)propyl]fluorene-9-carboxamide
Drug Type
Small molecular drug
Indication Dysrhythmias [ICD9: 427; ICD10:I47-I49] Approved [538531]
Therapeutic Class
Antidysrhythmic Agents
Company
Eli Lilly And Co
Structure
Download
2D MOL

3D MOL
Formula
C20H24N2O
Canonical SMILES
CC(C)NCCCC1(C2=CC=CC=C2C3=CC=CC=C31)C(=O)N
InChI
1S/C20H24N2O/c1-14(2)22-13-7-12-20(19(21)23)17-10-5-3-8-15(17)16-9-4-6-11-18(16)20/h3-6,8-11,14,22H,7,12-13H2,1-2H3,(H2,21,23)
InChIKey
UCEWGESNIULAGX-UHFFFAOYSA-N
CAS Number
CAS 74517-78-5
PubChem Compound ID
52195
PubChem Substance ID
8182440, 12012957, 14825601, 34716458, 46506714, 50065149, 57313452, 80483356, 104299011, 126419476, 126666697, 129347520, 134223780, 134337796, 135049274, 137007335, 160963540, 170465192, 179151066, 198983189, 223680424, 224830588, 226492697, 241134022, 242111131, 252543206
Target and Pathway
Target(s) Sodium channel protein type 5 subunit alpha Target Info Blocker [537786]
KEGG Pathway Adrenergic signaling in cardiomyocytes
PathWhiz Pathway Muscle/Heart Contraction
Reactome Interaction between L1 and Ankyrins
WikiPathways SIDS Susceptibility Pathways
Cardiac Progenitor Differentiation
References
Ref 538531FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019693.
Ref 537786Electrophysiological studies of indecainide hydrochloride, a new antiarrhythmic agent, in canine cardiac tissues. J Cardiovasc Pharmacol. 1984 Jul-Aug;6(4):614-21.

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