Drug Information

Drug General Information
Drug ID
D0K4HG
Former ID
DNC004366
Drug Name
8-(3-Nitro-phenyl)-6-pyridin-4-ylmethyl-quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525895]
Structure
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2D MOL

3D MOL
Formula
C21H15N3O2
Canonical SMILES
C1=CC(=CC(=C1)[N+](=O)[O-])C2=C3C(=CC(=C2)CC4=CC=NC=C4)<br />C=CC=N3
InChI
1S/C21H15N3O2/c25-24(26)19-5-1-3-17(14-19)20-13-16(11-15-6-9-22-10-7-15)12-18-4-2-8-23-21(18)20/h1-10,12-14H,11H2
InChIKey
XRSKAWJXBDACRF-UHFFFAOYSA-N
PubChem Compound ID
9819356
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [525895]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).

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