Drug General Information
Drug ID
D0K5UH
Former ID
DNC014548
Drug Name
CR-1795
Drug Type
Small molecular drug
Indication Discovery agent Terminated [546448]
Structure
Download
2D MOL

3D MOL

Formula
C27H38N2O4
Canonical SMILES
CCCCCN(CCCCC)C(=O)C(CCCC(=O)O)NC(=O)C1=CC2=CC=CC=C2C=C1
InChI
1S/C27H38N2O4/c1-3-5-9-18-29(19-10-6-4-2)27(33)24(14-11-15-25(30)31)28-26(32)23-17-16-21-12-7-8-13-22(21)20-23/h7-8,12-13,16-17,20,24H,3-6,9-11,14-15,18-19H2,1-2H3,(H,28,32)(H,30,31)/t24-/m1/s1
InChIKey
VHCOMPFCZPOZFX-XMMPIXPASA-N
PubChem Compound ID
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Inhibitor [551253]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 546448Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008170)
Ref 551253Biological properties of (R)-4-benzamido-5-oxopentanoic basic derivatives as CCK-antagonists, Bioorg. Med. Chem. Lett. 3(5):861-866 (1993).

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