Drug Information

Drug General Information
Drug ID
D0K6XD
Former ID
DNC007817
Drug Name
4-(1H-indol-4-yloxy)-1-(isopropylamino)butan-2-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529018]
Structure
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2D MOL

3D MOL
Formula
C15H22N2O2
Canonical SMILES
CC(C)NCC(CCOC1=CC=CC2=C1C=CN2)O
InChI
1S/C15H22N2O2/c1-11(2)17-10-12(18)7-9-19-15-5-3-4-14-13(15)6-8-16-14/h3-6,8,11-12,16-18H,7,9-10H2,1-2H3
InChIKey
DJWOTJGQRBWXIN-UHFFFAOYSA-N
PubChem Compound ID
44433256
Target and Pathway
Target(s) 5-hydroxytryptamine 1A receptor Target Info Inhibitor [529018]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
SIDS Susceptibility Pathways
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.
Ref 529018Bioorg Med Chem Lett. 2007 Oct 15;17(20):5600-4. Epub 2007 Aug 22.Indoloxypropanolamine analogues as 5-HT(1A) receptor antagonists.

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