Drug Information

Drug General Information
Drug ID
D0K9MT
Former ID
DNC004547
Drug Name
5-Isopropyl-3-(2-pyrrolidin-1-yl-ethyl)-1H-indole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525845]
Structure
Download
2D MOL

3D MOL
Formula
C17H24N2
Canonical SMILES
CC(C)C1=CC2=C(C=C1)NC=C2CCN3CCCC3
InChI
1S/C17H24N2/c1-13(2)14-5-6-17-16(11-14)15(12-18-17)7-10-19-8-3-4-9-19/h5-6,11-13,18H,3-4,7-10H2,1-2H3
InChIKey
BCHGFZYQLYUXBO-UHFFFAOYSA-N
PubChem Compound ID
10912152
Target and Pathway
Target(s) 5-hydroxytryptamine 1D receptor Target Info Inhibitor [525845]
5-hydroxytryptamine 1B receptor Target Info Inhibitor [525845]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04024:cAMP signaling pathway
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP722:Serotonin HTR1 Group and FOS Pathway
GPCR downstream signaling
References
Ref 525845Bioorg Med Chem Lett. 2000 Aug 7;10(15):1707-9.5-Alkyltryptamine derivatives as highly selective and potent 5-HT1D receptor agonists.
Ref 525845Bioorg Med Chem Lett. 2000 Aug 7;10(15):1707-9.5-Alkyltryptamine derivatives as highly selective and potent 5-HT1D receptor agonists.

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