Drug Information

Drug General Information
Drug ID
D0KQ9H
Former ID
DNC003685
Drug Name
L-747201
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534500]
Structure
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2D MOL

3D MOL
Formula
C16H19N5
Canonical SMILES
C1CCN(C1)CCC2=CNC3=C2C=C(C=C3)N4C=NN=C4
InChI
1S/C16H19N5/c1-2-7-20(6-1)8-5-13-10-17-16-4-3-14(9-15(13)16)21-11-18-19-12-21/h3-4,9-12,17H,1-2,5-8H2
InChIKey
WYXPLVWYFDBFBS-UHFFFAOYSA-N
PubChem Compound ID
10468938
Target and Pathway
Target(s) 5-hydroxytryptamine 1B receptor Target Info Inhibitor [534500]
5-hydroxytryptamine 1D receptor Target Info Inhibitor [534500]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapsehsa04024:cAMP signaling pathway
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling eventsR-HSA-390666:Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signalingWP722:Serotonin HTR1 Group and FOS Pathway
GPCR downstream signaling
References
Ref 534500J Med Chem. 1997 Oct 24;40(22):3501-3.Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.
Ref 534500J Med Chem. 1997 Oct 24;40(22):3501-3.Selective, orally active 5-HT1D receptor agonists as potential antimigraine agents.

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