Drug General Information
Drug ID	D0KY9B
Former ID	DNC002965
Drug Name	5-Chloryl-2,4,6-Quinazolinetriamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[551393]
Structure		Download 2D MOL 3D MOL
Formula	C8H8ClN5
Canonical SMILES	C1=CC2=C(C(=C1N)Cl)C(=NC(=N2)N)N
InChI	1S/C8H8ClN5/c9-6-3(10)1-2-4-5(6)7(11)14-8(12)13-4/h1-2H,10H2,(H4,11,12,13,14)
InChIKey	JZWXVYNQIJJTKF-UHFFFAOYSA-N
PubChem Compound ID	152217
PubChem Substance ID	826353, 7805119, 7886652, 10251447, 46228661, 50554352, 91574545, 103165079, 104433097, 121276649, 125675148, 128351641, 135258710, 137030683, 162803478, 163353686, 216249364, 225000880, 227804240, 249529308
Target and Pathway
Target(s)	Dihydrofolate reductase	Target Info	Inhibitor	[551393]
PathWhiz Pathway	Folate Metabolism
	Pterine Biosynthesis
Reactome	E2F mediated regulation of DNA replication
	Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
	Metabolism of folate and pterines
	G1/S-Specific Transcription
References
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393	How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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