Drug Information

Drug General Information
Drug ID
D0L0NY
Former ID
DNC004370
Drug Name
6-Imidazol-1-ylmethyl-8-phenyl-quinoline
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525895]
Structure
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2D MOL

3D MOL
Formula
C19H15N3
Canonical SMILES
C1=CC=C(C=C1)C2=C3C(=CC(=C2)CN4C=CN=C4)C=CC=N3
InChI
1S/C19H15N3/c1-2-5-16(6-3-1)18-12-15(13-22-10-9-20-14-22)11-17-7-4-8-21-19(17)18/h1-12,14H,13H2
InChIKey
PBPLGORPOONLEQ-UHFFFAOYSA-N
PubChem Compound ID
10565073
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [525895]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addiction
Reactome DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
References
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).
Ref 525895J Med Chem. 2000 Oct 19;43(21):3820-3.Hunting the emesis and efficacy targets of PDE4 inhibitors: identification of the photoaffinity probe 8-(3-azidophenyl)-6- [(4-iodo-1H-1-imidazolyl)methyl]quinoline (APIIMQ).

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