Drug Information

Drug General Information
Drug ID
D0LC2B
Former ID
DIB016194
Drug Name
NSP-805
Synonyms
TZN-01; 5-Methyl-6-[4-(2-methyl-3-oxo-1-cyclopentenylamino)phenyl]-2,3,4,5-tetrahydropyridazin-3-one
Drug Type
Small molecular drug
Indication Heart failure [ICD9: 428; ICD10:I50] Discontinued in Phase 2 [545097]
Structure
Download
2D MOL

3D MOL
Formula
C17H19N3O2
Canonical SMILES
CC1CC(=O)NN=C1C2=CC=C(C=C2)NC3=C(C(=O)CC3)C
InChI
1S/C17H19N3O2/c1-10-9-16(22)19-20-17(10)12-3-5-13(6-4-12)18-14-7-8-15(21)11(14)2/h3-6,10,18H,7-9H2,1-2H3,(H,19,22)
InChIKey
DSRIICXPBQXOKK-UHFFFAOYSA-N
CAS Number
CAS 125068-54-4
PubChem Compound ID
130349
PubChem Substance ID
10242587, 14873618, 29308976, 50622140, 57343370, 104372599, 126436849, 134222472, 135086460, 162383372, 162782518, 224944990, 232981790
Target and Pathway
Target(s) Phosphodiesterase (PDE) 3 Target Info Modulator
References
Ref 545097Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002110)

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