Drug Information

Drug General Information
Drug ID
D0LT5D
Former ID
DNC010463
Drug Name
(R)-8-phenyl-N,N-dipropylchroman-3-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530699]
Structure
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2D MOL

3D MOL
Formula
C21H27NO
Canonical SMILES
CCCN(CCC)C1CC2=CC=CC(=C2OC1)C3=CC=CC=C3
InChI
1S/C21H27NO/c1-3-13-22(14-4-2)19-15-18-11-8-12-20(21(18)23-16-19)17-9-6-5-7-10-17/h5-12,19H,3-4,13-16H2,1-2H3/t19-/m1/s1
InChIKey
OYEKUFKQGCYWCG-LJQANCHMSA-N
PubChem Compound ID
11267988
Target and Pathway
Target(s) 5-hydroxytryptamine 7 receptor Target Info Inhibitor [530699]
KEGG Pathway Ras signaling pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome Serotonin receptors
G alpha (s) signalling events
WikiPathways Serotonin Receptor 4/6/7 and NR3C Signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.
Ref 530699Bioorg Med Chem. 2010 Mar 1;18(5):1958-67. Epub 2010 Jan 18.SAR studies on new bis-aryls 5-HT7 ligands: Synthesis and molecular modeling.

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