Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0M7LV
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| Former ID |
DNC008882
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| Drug Name |
LYSERGIC ACID DIETHYLAMIDE
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| Drug Type |
Small molecular drug
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| Structure |
|
Download2D MOL |
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| Formula |
C20H25N3O
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| InChI |
InChI=1S/C20H25N3O/c1-4-23(5-2)20(24)14-9-16-15-7-6-8-17-19(15)13(11-21-17)10-18(16)22(3)12-14/h6-9,11,14,18,21H,4-5,10,12H2,1-3H3/t14-,18-/m1/s1
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| InChIKey |
VAYOSLLFUXYJDT-RDTXWAMCSA-N
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| CAS Number |
CAS 50-37-3
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| PubChem Compound ID | |||||
| PubChem Substance ID |
9745, 841062, 7979834, 8153537, 15470164, 15976361, 24896390, 29224797, 46506397, 46530543, 47216998, 47589197, 47810991, 48185195, 48416190, 49689414, 49965400, 50113078, 57322936, 76084429, 103164236, 104098839, 104310181, 124893452, 127253497, 127253498, 127253499, 127253500, 127253501, 127253502, 127253503, 127253504, 127253505, 127253506, 127253507, 127253508, 127253509, 127253510, 127253511, 127253512, 127253513, 127253514, 127253515, 127253516, 127253517, 127253518, 127253519, 127253520, 127253521, 127253522
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 1A receptor | Target Info | Inhibitor | [533701] | |
| 5-hydroxytryptamine 2A receptor | Target Info | Inhibitor | [528294] | ||
| WikiPathways | Serotonin HTR1 Group and FOS Pathway | ||||
| SIDS Susceptibility Pathways | |||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP733:Serotonin Receptor 2 and STAT3 Signaling | |||||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | |||||
| Gastrin-CREB signalling pathway via PKC and MAPK | |||||
| GPCR downstream signaling | |||||
| GPCRs, Other | |||||
| References | |||||
| Ref 526769 | Psychopathology and psychophysiology of minimal LSD-25 dosage; a preliminary dosage-response spectrum. AMA Arch Neurol Psychiatry. 1958 Feb;79(2):208-10. | ||||
| Ref 539053 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 17). | ||||
| Ref 528294 | J Med Chem. 2006 Jul 13;49(14):4269-74.C-(4,5,6-trimethoxyindan-1-yl)methanamine: a mescaline analogue designed using a homology model of the 5-HT2A receptor. | ||||
| Ref 533701 | J Med Chem. 1995 Mar 17;38(6):958-66.Stereoselective LSD-like activity in a series of d-lysergic acid amides of (R)- and (S)-2-aminoalkanes. | ||||
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