Drug Information

Drug General Information
Drug ID
D0M9GE
Former ID
DPR000097
Drug Name
Rimcazole
Synonyms
Rimcazol; Rimcazolum; Rimcazole [INN]; BW 234U; BW-234U; Rimcazol [INN-Spanish]; Rimcazolum [INN-Latin]; Cis-9-(3-(3,5-dimethyl-1-piperazinyl)propyl)carbazole; 9-[3-(Cis-3,5-Dimethyl-1-Piperazinyl)Propyl]Carbazole Hydrochloride; 9-[3-(cis-3,5-Dimethyl-1-piperazinyl)propyl]carbazole dihydrochloride monohydrate; 9-[3-[(3R,5S)-3,5-dimethylpiperazin-1-yl]propyl]carbazole; 9-[3-[(3S,5R)-3,5-dimethylpiperazin-1-yl]propyl]carbazole
Drug Type
Small molecular drug
Indication Schizophrenia [ICD9: 295; ICD10:F20] Terminated [536463]
Company
GlaxoSmithKline
Structure
Download
2D MOL

3D MOL
Formula
C21H27N3
Canonical SMILES
CC1CN(CC(N1)C)CCCN2C3=CC=CC=C3C4=CC=CC=C42
InChI
1S/C21H27N3/c1-16-14-23(15-17(2)22-16)12-7-13-24-20-10-5-3-8-18(20)19-9-4-6-11-21(19)24/h3-6,8-11,16-17,22H,7,12-15H2,1-2H3/t16-,17+
InChIKey
GUDVQJXODNJRIJ-CALCHBBNSA-N
CAS Number
CAS 75859-04-0
PubChem Compound ID
53389
PubChem Substance ID
8183092, 11114108, 14826188, 14850557, 34717484, 50065163, 50751133, 57313521, 103173857, 103930665, 104302073, 117393911, 117393912, 128006689, 134224692, 135049276, 142134170, 163660471, 179151095, 198963611, 224844315, 226474548, 252450934
Target and Pathway
Target(s) Sigma(1)-type opioid receptor Target Info Antagonist [536463]
WikiPathways miR-targeted genes in squamous cell - TarBase
miR-targeted genes in lymphocytes - TarBase
References
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.
Ref 536463The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.

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