Drug Information

Drug General Information
Drug ID
D0MH8O
Former ID
DIB009302
Drug Name
Angiotensin-(1-7)
Synonyms
Ang (1-7); Angiotensin (1-7); Angiotensin-(1-7) (cancer); Angiotensin-(1-7) (cancer), Wake Forest University
Drug Type
Small molecular drug
Indication Sarcoma [ICD9: 202.8; ICD10:C81-C86] Phase 3 [532124], [541138]
Company
Tarix pharmaceuticals
Structure
Download
2D MOL

3D MOL
Formula
C41H62N12O11
InChI
InChI=1S/C41H62N12O11/c1-5-22(4)33(38(61)50-29(17-24-19-45-20-47-24)39(62)53-15-7-9-30(53)40(63)64)52-36(59)28(16-23-10-12-25(54)13-11-23)49-37(60)32(21(2)3)51-35(58)27(8-6-14-46-41(43)44)48-34(57)26(42)18-31(55)56/h10-13,19-22,26-30,32-33,54H,5-9,14-18,42H2,1-4H3,(H,45,47)(H,48,57)(H,49,60)(H,50,61)(H,51,58)(H,52,59)(H,55,56)(H,63,64)(H4,43,44,46)/t22-,26-,27-,28-,29-,30-,32-,33-/m0/s1
InChIKey
PVHLMTREZMEJCG-GDTLVBQBSA-N
PubChem Compound ID
123805
PubChem Substance ID
14889691, 14938661, 29303996, 47205170, 50070389, 50070541, 50071317, 50112515, 74375902, 80118902, 87351979, 104419365, 126686943, 134223321, 135079217, 135232468, 135651614, 136351656, 137156831, 163423858, 184605749, 223672217, 240852277, 241091408, 241182531, 241375500, 249617335, 252392657, 252477658
Target and Pathway
Target(s) Proto-oncogene Mas Target Info Agonist [532124]
KEGG Pathway Neuroactive ligand-receptor interaction
Renin-angiotensin system
WikiPathways ACE Inhibitor Pathway
GPCRs, Class A Rhodopsin-like
References
Ref 532124New therapeutic pathways in the RAS. J Renin Angiotensin Aldosterone Syst. 2012 Dec;13(4):505-8.
Ref 541138(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 582).
Ref 532124New therapeutic pathways in the RAS. J Renin Angiotensin Aldosterone Syst. 2012 Dec;13(4):505-8.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.