TTD | Drug: D0MS0A

Drug General Information
Drug ID	D0MS0A
Former ID	DNC001294
Drug Name	SB 656104-A
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[535905]
Structure		Download 2D MOL 3D MOL
Formula	C28H31NO7-2
Canonical SMILES	COC1=C(C=C2C(=C1)CC(C2=O)CC3CCN(CC3)CC4=CC=CC=C4)OC.C(=<br />CC(=O)[O-])C(=O)[O-]
InChI	1S/C24H29NO3.C4H4O4/c1-27-22-14-19-13-20(24(26)21(19)15-23(22)28-2)12-17-8-10-25(11-9-17)16-18-6-4-3-5-7-18;5-3(6)1-2-4(7)8/h3-7,14-15,17,20H,8-13,16H2,1-2H3;1-2H,(H,5,6)(H,7,8)/p-2/b;2-1+
InChIKey	APUVNJQYQMJLQQ-WLHGVMLRSA-L
CAS Number	CAS 147025-54-5
PubChem Compound ID	24801487
PubChem Substance ID	49746076, 57118411, 134339030, 134340289, 134340319, 134340500, 224456767
Target and Pathway
Target(s)	5-hydroxytryptamine 7 receptor	Target Info	Antagonist	[535905]
KEGG Pathway	Ras signaling pathway
	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 7 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 535905	5-HT7 receptors. Curr Drug Targets CNS Neurol Disord. 2004 Feb;3(1):81-90.
Ref 535905	5-HT7 receptors. Curr Drug Targets CNS Neurol Disord. 2004 Feb;3(1):81-90.

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Drug Information