Drug Information

Drug General Information
Drug ID
D0MZ9A
Former ID
DIB012363
Drug Name
Suronacrine maleate
Synonyms
HP-128; Suronacrine maleate < Rec INNM; Rac-9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol maleate
Drug Type
Small molecular drug
Indication Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3] Phase 3 [551848]
Structure
Download
2D MOL

3D MOL
Formula
C24H24N2O5
Canonical SMILES
OC1CCCc2nc3ccccc3c(NCc4ccccc4)c12
InChI
1S/C20H20N2O/c23-18-12-6-11-17-19(18)20(15-9-4-5-10-16(15)22-17)21-13-14-7-2-1-3-8-14/h1-5,7-10,18,23H,6,11-13H2,(H,21,22)
InChIKey
HERUZAOANPGYSY-UHFFFAOYSA-N
CAS Number
CAS 113108-86-4
PubChem Compound ID
9953907
Target and Pathway
Target(s) Sodium-dependent noradrenaline transporter Target Info Modulator
Acetylcholinesterase Target Info Modulator
KEGG Pathway Glycerophospholipid metabolism
Cholinergic synapse
PANTHER Pathway Adrenaline and noradrenaline biosynthesisP00042:Muscarinic acetylcholine receptor 1 and 3 signaling pathway
Muscarinic acetylcholine receptor 2 and 4 signaling pathway
Nicotinic acetylcholine receptor signaling pathway
Pathway Interaction Database ATF-2 transcription factor network
PathWhiz Pathway Phospholipid Biosynthesis
Reactome Na+/Cl- dependent neurotransmitter transporters
WikiPathways Monoamine Transport
NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compoundsWP727:Monoamine Transport
Biogenic Amine Synthesis
Acetylcholine Synthesis
Integrated Pancreatic Cancer Pathway
References
Ref 551848Handbook of Dementing Illnesses, Morris John. Page(570).

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