Drug Information

Drug General Information
Drug ID
D0N0ES
Former ID
DAP001546
Drug Name
Vitamin B3
Synonyms
Niacin (TN); Niacinamide (TN); Nicotinamide (TN)
Drug Type
Small molecular drug
Indication Lipid disorder; Cardiovascular disease [ICD9: 272, 390-459; ICD10:E78, I00-I99] Approved [526373]
Company
Anmar
Structure
Download
2D MOL

3D MOL
Formula
C6H4NO2-
Canonical SMILES
C1=CC(=CN=C1)C(=O)O
InChI
1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)/i1D,2D,3D,4D
InChIKey
PVNIIMVLHYAWGP-RHQRLBAQSA-N
CAS Number
CAS 59-67-6
PubChem Compound ID
937
Target and Pathway
Target(s) Diacylglycerol O-acyltransferase 2 Target Info Inhibitor [526373]
Nicotinic acid receptor Target Info Agonist [526373]
BioCyc Pathway Triacylglycerol biosynthesis
KEGG Pathway Glycerolipid metabolism
Metabolic pathways
Fat digestion and absorption
Reactome Acyl chain remodeling of DAG and TAG
Triglyceride Biosynthesis
WikiPathways Triacylglyceride Synthesis
Glycerophospholipid biosynthesis
Fatty acid, triacylglycerol, and ketone body metabolism
References
Ref 526373Hakozaki T, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy RE: The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 2002 Jul;147(1):20-31.
Ref 526373Hakozaki T, Minwalla L, Zhuang J, Chhoa M, Matsubara A, Miyamoto K, Greatens A, Hillebrand GG, Bissett DL, Boissy RE: The effect of niacinamide on reducing cutaneous pigmentation and suppression of melanosome transfer. Br J Dermatol. 2002 Jul;147(1):20-31.

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