Drug Information

Drug General Information
Drug ID
D0N2WK
Former ID
DIB019668
Drug Name
CV-3988
Synonyms
CV 3988; CV3988
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541325]
Structure
Download
2D MOL
Formula
C28H53N2O7PS
InChI
InChI=1S/C28H53N2O7PS/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-29-28(31)35-24-27(34-2)25-37-38(32,33)36-22-20-30-21-23-39-26-30/h21,23,26-27H,3-20,22,24-25H2,1-2H3,(H-,29,31,32,33)
InChIKey
NMHKTASGTFXJPL-UHFFFAOYSA-N
PubChem Compound ID
107681
PubChem Substance ID
10234383, 12013001, 14911658, 17405616, 24278829, 44436655, 50065317, 50106962, 50111231, 53778166, 57338181, 74605260, 85230979, 90340573, 92303175, 103119908, 103225045, 103919472, 104379471, 117576833, 124750208, 124879724, 126431481, 135062669, 135727620, 163110452, 163565014, 178102700, 179293951, 234184627
Target and Pathway
Target(s) Platelet-activating factor receptor Target Info Antagonist [533398]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Staphylococcus aureus infection
NetPath Pathway IL5 Signaling Pathway
Leptin Signaling Pathway
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (q) signalling events
Interferon gamma signaling
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Small Ligand GPCRs
Interferon gamma signaling
GPCR ligand binding
GPCR downstream signaling
References
Ref 541325(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6079).
Ref 533398Inhibition by CV-3988 of the binding of [3H]-platelet activating factor (PAF) to the platelet. Biochem Pharmacol. 1985 May 1;34(9):1491-5.

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