TTD | Drug: D0N4RO

Drug General Information
Drug ID	D0N4RO
Former ID	DIB019308
Drug Name	compound 1b
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529216]
Structure		Download 2D MOL
Formula	C24H23NO3S
InChI	InChI=1S/C24H23NO3S/c26-23(22(29)16-17-7-3-1-4-8-17)25-21(24(27)28)15-18-11-13-20(14-12-18)19-9-5-2-6-10-19/h1-14,21-22,29H,15-16H2,(H,25,26)(H,27,28)/t21-,22+/m0/s1
InChIKey	BNECOBGISSOLPT-FCHUYYIVSA-N
PubChem Compound ID	44377139
PubChem Substance ID	103416944, 104128295, 252166827
Target and Pathway
Target(s)	Neutral endopeptidase	Target Info	Inhibitor	[529216]
Target(s)	Carboxypeptidase A1 (pancreatic)	Target Info	Inhibitor	[529216]
KEGG Pathway	Renin-angiotensin system
	Hematopoietic cell lineage
	Protein digestion and absorption
	Alzheimer's disease
NetPath Pathway	EGFR1 Signaling Pathway
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
Reactome	Metabolism of Angiotensinogen to Angiotensins
WikiPathways	Metabolism of Angiotensinogen to Angiotensins
	Primary Focal Segmental Glomerulosclerosis FSGS
	Alzheimers Disease
References
Ref 529216	Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett. 2008 Jan 15;18(2):732-7. Epub 2007 Nov 19.
Ref 529216	Thiol-based angiotensin-converting enzyme 2 inhibitors: P1 modifications for the exploration of the S1 subsite. Bioorg Med Chem Lett. 2008 Jan 15;18(2):732-7. Epub 2007 Nov 19.

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Drug Information