Drug General Information
Drug ID
D0N9ON
Former ID
DNC009303
Drug Name
KNI-10092
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529771]
Structure
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2D MOL

3D MOL

Formula
C34H39N3O7S
Canonical SMILES
CC1(C(N(CS1)C(=O)C(C(CC2=CC=CC=C2)NC(=O)COC3=CC=CC=C3OC<br />)O)C(=O)NC4C(CC5=CC=CC=C45)O)C
InChI
1S/C34H39N3O7S/c1-34(2)31(32(41)36-29-23-14-8-7-13-22(23)18-25(29)38)37(20-45-34)33(42)30(40)24(17-21-11-5-4-6-12-21)35-28(39)19-44-27-16-10-9-15-26(27)43-3/h4-16,24-25,29-31,38,40H,17-20H2,1-3H3,(H,35,39)(H,36,41)/t24-,25+,29-,30-,31+/m0/s1
InChIKey
JFCIKXOPSCFWBJ-ZNIFFWLPSA-N
PubChem Compound ID
Target and Pathway
Target(s) Plasmepsin 2 Target Info Inhibitor [529771]
References
Ref 529771Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. Epub 2008 Oct 10.Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin.
Ref 529771Bioorg Med Chem. 2008 Dec 1;16(23):10049-60. Epub 2008 Oct 10.Antimalarial activity enhancement in hydroxymethylcarbonyl (HMC) isostere-based dipeptidomimetics targeting malarial aspartic protease plasmepsin.

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