Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0NA7G
|
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| Former ID |
DNC006840
|
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| Drug Name |
MCL-451
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [528412] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C24H29N3O5
|
||||
| Canonical SMILES |
CC1=CC(=CC(=C1CC(C(=O)N2CC3=CC=CC=C3CC2C(=O)NCCC(=O)O)N<br />)C)O
|
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| InChI |
1S/C24H29N3O5/c1-14-9-18(28)10-15(2)19(14)12-20(25)24(32)27-13-17-6-4-3-5-16(17)11-21(27)23(31)26-8-7-22(29)30/h3-6,9-10,20-21,28H,7-8,11-13,25H2,1-2H3,(H,26,31)(H,29,30)/t20-,21-/m0/s1
|
||||
| InChIKey |
FEJBKZCTAXWTTN-SFTDATJTSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Kappa-type opioid receptor | Target Info | Inhibitor | [528412] | |
| Delta-type opioid receptor | Target Info | Inhibitor | [528412] | ||
| Mu-type opioid receptor | Target Info | Inhibitor | [528412] | ||
| NetPath Pathway | TCR Signaling Pathway | ||||
| PANTHER Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Opioid prodynorphin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Enkephalin release | |||||
| Opioid proenkephalin pathway | |||||
| Opioid proopiomelanocortin pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||||
| Pathway Interaction Database | IL4-mediated signaling events | ||||
| References | |||||
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