Drug General Information
Drug ID	D0ND9T
Former ID	DNCL002537
Drug Name	CRLX101
Indication	Late-stage solid tumors [ICD9: 140-199, 210-229; ICD10:C00-C75, C7A, C7B, D10-D36, D3A]		Phase 2	[524225]
Company	Cerulean Pharma
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Toposisomerase-1	Target Info	Modulator
NetPath Pathway	IL2 Signaling Pathway
PANTHER Pathway	DNA replication
Pathway Interaction Database	Caspase Cascade in Apoptosis
WikiPathways	Integrated Pancreatic Cancer Pathway
References
Ref 524225	ClinicalTrials.gov (NCT01803269) Topotecan Hydrochloride or Cyclodextrin-Based Polymer-Camptothecin CRLX101 in Treating Patients With Recurrent Small Cell Lung Cancer. U.S. National Institutes of Health.

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