Drug General Information
Drug ID	D0NF7S
Former ID	DIB012032
Drug Name	R-59494
Drug Type	Small molecular drug
Indication	Ischemia [ICD9: 459.89; ICD10:I99.8]		Terminated	[545149]
Company	Janssen Pharmaceutica NV
Structure		Download 2D MOL 3D MOL
Formula	C22H23N3OS
Canonical SMILES	c1(nc2c(s1)cccc2)N(C1CN(CC1)CCCCOc1ccccc1)C
CAS Number	CAS 104588-44-5
PubChem Compound ID	132007
Target and Pathway
Target(s)	Sodium channel	Target Info	Modulator	[526753]
KEGG Pathway	Dopaminergic synapse
Reactome	Interaction between L1 and Ankyrins
References
Ref 545149	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002300)
Ref 526753	Veratridine activates a silent sodium channel in rat isolated aorta. Eur J Pharmacol. 1992 Aug 25;219(2):253-9.

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