Drug Information

Drug General Information
Drug ID
D0NS1X
Former ID
DIB002732
Drug Name
SAR-650984
Synonyms
Anti-CD38 monoclonal antibody (leukemia), ImmunoGen/sanofi-aventis
Drug Type
Antibody
Indication Hematological malignancies [ICD9: 200-209; ICD10:C81-C86] Phase 1/2 [522969]
Company
ImmunoGen Inc
Target and Pathway
Target(s) CD38 Target Info [551980]
KEGG Pathway Nicotinate and nicotinamide metabolism
Metabolic pathways
Calcium signaling pathway
Hematopoietic cell lineage
Oxytocin signaling pathway
Salivary secretion
Pancreatic secretion
Epstein-Barr virus infection
NetPath Pathway Leptin Signaling Pathway
TCR Signaling Pathway
PANTHER Pathway CCKR signaling map ST
WikiPathways Oxytocin signaling
References
Ref 522969ClinicalTrials.gov (NCT01084252) Phase 1/2 Dose Escalation and Efficacy Study of Anti-CD38 Monoclonal Antibody in Patients With Selected CD38+ Hematological Malignancies. U.S. National Institutes of Health.
Ref 551980Clinical pipeline report, company report or official report of Sanofi-Aventis.

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