Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0O0RY
|
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| Former ID |
DNC000826
|
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| Drug Name |
JB-1
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Multiple myeloma [ICD9: 203; ICD10:C90] | Investigative | [537114] | ||
| Company |
Chiron
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C28H50O3
|
||||
| Canonical SMILES |
CCCCC(CCO)C(C)C1CCC2C1(CCCC2CCC3=C(C(CC(C3)O)O)C)C
|
||||
| InChI |
1S/C28H50O3/c1-5-6-8-21(14-16-29)19(2)25-12-13-26-22(9-7-15-28(25,26)4)10-11-23-17-24(30)18-27(31)20(23)3/h19,21-22,24-27,29-31H,5-18H2,1-4H3/t19-,21+,22?,24-,25-,26+,27+,28-/m1/s1
|
||||
| InChIKey |
DHZOGFADXFKXSH-PMMQCNKASA-N
|
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| CAS Number |
CAS 78617-10-4
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Insulin-like growth factor I receptor | Target Info | Inhibitor | [537114] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| FoxO signaling pathway | |||||
| Oocyte meiosis | |||||
| Endocytosis | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Focal adhesion | |||||
| Adherens junction | |||||
| Signaling pathways regulating pluripotency of stem cells | |||||
| Long-term depression | |||||
| Ovarian steroidogenesis | |||||
| Progesterone-mediated oocyte maturation | |||||
| Pathways in cancer | |||||
| Transcriptional misregulation in cancer | |||||
| Proteoglycans in cancer | |||||
| Glioma | |||||
| Prostate cancer | |||||
| Melanoma | |||||
| References | |||||
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