Drug General Information
Drug ID	D0O8PM
Former ID	DNC007637
Drug Name	N,N-bis(cyanomethyl)-3,4-dimethoxybenzamide
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529037]
Structure		Download 2D MOL 3D MOL
Formula	C13H13N3O3
Canonical SMILES	COC1=C(C=C(C=C1)C(=O)N(CC#N)CC#N)OC
InChI	1S/C13H13N3O3/c1-18-11-4-3-10(9-12(11)19-2)13(17)16(7-5-14)8-6-15/h3-4,9H,7-8H2,1-2H3
InChIKey	GZUJYYKDHAQDKU-UHFFFAOYSA-N
PubChem Compound ID	669334
Target and Pathway
Target(s)	Leukocyte elastase	Target Info	Inhibitor	[529037]
KEGG Pathway	Transcriptional misregulation in cancer
	Systemic lupus erythematosus
Pathway Interaction Database	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
	C-MYB transcription factor network
Reactome	Collagen degradation
	Degradation of the extracellular matrix
	Activation of Matrix Metalloproteinases
WikiPathways	Hair Follicle Development: Cytodifferentiation (Part 3 of 3)
	Human Complement System
	Degradation of collagen
References
Ref 529037	J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.
Ref 529037	J Med Chem. 2007 Oct 4;50(20):4928-38. Epub 2007 Sep 12.N-benzoylpyrazoles are novel small-molecule inhibitors of human neutrophil elastase.

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