Drug General Information
Drug ID	D0OP7B
Former ID	DIB002106
Drug Name	LY-210073
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Terminated	[534014]
Company	Eli Lilly & Co
Structure		Download 2D MOL 3D MOL
Formula	C30H28O8
Canonical SMILES	c12c(c(=O)c3c(o1)ccc(c3)C(=O)O)ccc(c2CCC(=O)O)OCCCC/C=C<br />/c1ccc(cc1)OC
CAS Number	CAS 148291-65-0
PubChem Compound ID	6450158
Target and Pathway
Target(s)	Leukotriene B4 receptor 1	Target Info	Modulator	[534014]
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
Reactome	Leukotriene receptors
	G alpha (q) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 534014	Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.
Ref 534014	Design, synthesis, and pharmacological evaluation of potent xanthone dicarboxylic acid leukotriene B4 receptor antagonists. J Med Chem. 1993 Jun 11;36(12):1726-34.

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