Drug General Information
Drug ID	D0OQ4H
Former ID	DIB014129
Drug Name	A-69024
Drug Type	Small molecular drug
Indication	Psychotic disorders [ICD9: 290-299; ICD10:F20-F29]		Terminated	[545268]
Company	Abbott Laboratories
Structure		Download 2D MOL 3D MOL
Formula	C20H24BrNO4
Canonical SMILES	c12C(N(CCc1cc(c(c2)O)OC)C)Cc1c(cc(c(c1)OC)OC)Br
CAS Number	CAS 58939-37-0
PubChem Compound ID	173657
Target and Pathway
Target(s)	Dopamine D1 receptor	Target Info	Modulator	[526304]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Morphine addiction
	Alcoholism
PANTHER Pathway	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Dopamine Activation of Neurological Reward System
Reactome	Dopamine receptors
	G alpha (s) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545268	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002637)
Ref 526304	(+)-[76Br]A-69024: a non-benzazepine radioligand for studies of dopamine D1 receptors using PET. Nucl Med Biol. 2002 Apr;29(3):295-302.

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