Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D0OT9B
|
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| Former ID |
DIB020191
|
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| Drug Name |
L-aspartic acid
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| Synonyms |
L-Asp; L-aspartate; Aspatofort
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [540269] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C4H7NO4
|
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| InChI |
InChI=1S/C4H7NO4/c5-2(4(8)9)1-3(6)7/h2H,1,5H2,(H,6,7)(H,8,9)/t2-/m0/s1
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| InChIKey |
CKLJMWTZIZZHCS-REOHCLBHSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID |
3351, 627127, 820598, 820604, 821992, 823680, 824125, 827788, 830716, 841716, 7847081, 7885984, 8025800, 8144794, 8153703, 10318344, 10527673, 11109886, 11113409, 14710666, 15119963, 17404696, 24277948, 24698176, 24769862, 24770212, 24847046, 24890873, 24890976, 24891191, 24891385, 24902272, 26702710, 26705516, 26712266, 26712700, 26718511, 26751648, 29224983, 46507997, 47217068, 47365467, 47811039, 47960025, 48334792, 48415581, 48419498, 49746800, 49829767, 49856449
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| Target and Pathway | |||||
| Target(s) | Glutamate [NMDA] receptor subunit epsilon 1 | Target Info | Agonist | [543837] | |
| Glutamate [NMDA] receptor subunit epsilon 2 | Target Info | Agonist | [543838] | ||
| NMDA receptor subunit NR1 | Target Info | Agonist | [543836] | ||
| GluN2D | Target Info | Agonist | [543840] | ||
| GluN2C | Target Info | Agonist | [543839] | ||
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| Calcium signaling pathway | |||||
| cAMP signaling pathway | |||||
| Neuroactive ligand-receptor interaction | |||||
| Circadian entrainment | |||||
| Long-term potentiation | |||||
| Glutamatergic synapse | |||||
| Dopaminergic synapse | |||||
| Alzheimer's disease | |||||
| Amyotrophic lateral sclerosis (ALS) | |||||
| Cocaine addiction | |||||
| Amphetamine addiction | |||||
| Nicotine addiction | |||||
| Alcoholism | |||||
| Systemic lupus erythematosushsa04014:Ras signaling pathway | |||||
| Huntington's disease | |||||
| PANTHER Pathway | Huntington disease | ||||
| Ionotropic glutamate receptor pathway | |||||
| Metabotropic glutamate receptor group III pathway | |||||
| Metabotropic glutamate receptor group I pathway | |||||
| Muscarinic acetylcholine receptor 1 and 3 signaling pathwayP00029:Huntington disease | |||||
| Muscarinic acetylcholine receptor 1 and 3 signaling pathway | |||||
| Pathway Interaction Database | Reelin signaling pathwayerbb4_pathway:ErbB4 signaling events | ||||
| Reelin signaling pathway | |||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||||
| Alzheimers DiseaseWP666:Hypothetical Network for Drug Addiction | |||||
| BDNF signaling pathwayWP706:SIDS Susceptibility Pathways | |||||
| Spinal Cord Injury | |||||
| BDNF signaling pathway | |||||
| Alzheimers Disease | |||||
| References | |||||
| Ref 543836 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 455). | ||||
| Ref 543837 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 456). | ||||
| Ref 543838 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 457). | ||||
| Ref 543839 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 458). | ||||
| Ref 543840 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 459). | ||||
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