Drug General Information
Drug ID	D0OW1R
Former ID	DIB007144
Drug Name	YM-43611
Indication	Psychotic disorders [ICD9: 290-299; ICD10:F20-F29]		Terminated	[546030]
Company	Yamanouchi Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(C(=O)N[C@@H]2CN(Cc3ccccc3)CC2)c(cc(NC(=O)C2CC2)c(c1)<br />Cl)OC
CAS Number	CAS 169451-66-5
Target and Pathway
Target(s)	D(3) dopamine receptor	Target Info	Modulator
	D(4) dopamine receptor	Target Info	Modulator
KEGG Pathway	Neuroactive ligand-receptor interaction
	Dopaminergic synapsehsa04080:Neuroactive ligand-receptor interaction
	Dopaminergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Dopamine receptor mediated signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Dopamine receptors
	G alpha (i) signalling eventsR-HSA-390651:Dopamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
	GPCRs, OtherWP666:Hypothetical Network for Drug Addiction
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCRs, Other
References
Ref 546030	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800005975)

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