Drug Information

Drug General Information
Drug ID
D0P0KF
Former ID
DAP000672
Drug Name
Clobazam
Synonyms
Caastilium; Chlorepin; Clobazamum; Clorepin; Frisium; Mystan; Noiafren; Odipam; Urbadan; Urbanil; Urbanyl; H 4723; HR 376; LM 2717; Clobazamum [INN-Latin]; Frisium (TN); H-4723; LM-2717; Mystan (TN); RU-4723; Urbanol (TN); Clobazam [USAN:BAN:INN]; Clobazam (JAN/USAN/INN); 1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-diketo-3H-1,5-benzodiazepine; 1-Phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-dioxo-3H-1,5-benzodiazepine; 1-phenyl-5-methyl-8-chloro-1,2,4,5-tetrahydro-2,4-diketo-3H-1,5-benzodiazepine; 4(3H,5H)-dione; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4(3H,5H)-dione; 7-Chloro-1-methyl-5-phenyl-1H-1,5-benzodiazepine-2,4-(3H,5H)-dione; 7-chloro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4-dione
Drug Type
Small molecular drug
Indication Epilepsy; Anxiety disorder [ICD9: 300, 345; ICD10:F40-F42, G40] Approved [542156], [550702]
Therapeutic Class
Anticonvulsants
Company
Aventis Pharmaceuticals Inc.
Formula
C16H13ClN2O2
InChI
InChI=1S/C16H13ClN2O2/c1-18-13-8-7-11(17)9-14(13)19(16(21)10-15(18)20)12-5-3-2-4-6-12/h2-9H,10H2,1H3
InChIKey
CXOXHMZGEKVPMT-UHFFFAOYSA-N
CAS Number
CAS 22316-47-8
PubChem Compound ID
2789
PubChem Substance ID
225150, 460264, 5527869, 7848316, 7849655, 7978962, 8151800, 10514089, 15394984, 24893060, 29221944, 46506115, 49884044, 50113062, 53393433, 57321460, 58106913, 92719466, 92729853, 96079563, 103266846, 104301616, 119525695, 125536755, 126620779, 126666450, 127692535, 134337961, 134994740, 136949634, 137004939, 144206161, 160963696, 164788387, 175266088, 178103724, 179150176, 184529097, 198991795, 223366869, 223664749, 224787753, 226427583, 250115646, 252347507
SuperDrug ATC ID
N05BA09
SuperDrug CAS ID
cas=022316478
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Antagonist [536555]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 542156(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7149).
Ref 550702Drug information of Clobazam, 2008. eduDrugs.
Ref 536555DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. Epub 2007 Nov 29.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.