Drug Information

Drug General Information
Drug ID
D0P1QW
Former ID
DCL000715
Drug Name
Becampanel
Synonyms
AMP397; AMP-397; AMP-397A; [(7-nitro-2,3-dioxo-1,4-dihydroquinoxalin-5-yl)methylamino]methylphosphonic acid
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Discontinued in Phase 2 [536498]
Company
Novartis
Structure
Download
2D MOL

3D MOL
Formula
C10H11N4O7P
Canonical SMILES
C1=C(C=C(C2=C1NC(=O)C(=O)N2)CNCP(=O)(O)O)[N+](=O)[O-]
InChI
1S/C10H11N4O7P/c15-9-10(16)13-8-5(3-11-4-22(19,20)21)1-6(14(17)18)2-7(8)12-9/h1-2,11H,3-4H2,(H,12,15)(H,13,16)(H2,19,20,21)
InChIKey
ABFMMCZFKUIJGQ-UHFFFAOYSA-N
CAS Number
CAS 188696-80-2
PubChem Compound ID
5491960
PubChem Substance ID
11694476, 12015413, 14826627, 39474544, 57364645, 77702463, 103289490, 103967213, 113999338, 127381031, 134339214, 135165782, 137263457, 141003652, 163306140, 179322250, 198980733, 228506497
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Antagonist [536166], [536498]
References
Ref 536498Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.
Ref 536166Glutamate- and GABA-based CNS therapeutics. Curr Opin Pharmacol. 2006 Feb;6(1):7-17.
Ref 536498Emerging drugs for epilepsy. Expert Opin Emerg Drugs. 2007 Sep;12(3):407-22.

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