Drug General Information
Drug ID
D0P2DB
Former ID
DNC012321
Drug Name
7,12-Dihydro-5,7,12-triaza-indeno[1,2-a]fluorene
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533412]
Structure
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2D MOL

3D MOL

Formula
C17H11N3
Canonical SMILES
C1=CC=C2C(=C1)C3=C4C(=NC=C3N2)C5=CC=CC=C5N4
InChI
1S/C17H11N3/c1-3-7-12-10(5-1)15-14(19-12)9-18-16-11-6-2-4-8-13(11)20-17(15)16/h1-9,19-20H
InChIKey
UFTKNTUWDMJOIX-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor Target Info Inhibitor [533412]
Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533412]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533412J Med Chem. 1987 Mar;30(3):456-8.Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands.
Ref 533412J Med Chem. 1987 Mar;30(3):456-8.Synthesis of 7,12-dihydropyrido[3,4-b:5,4-b']diindoles. A novel class of rigid, planar benzodiazepine receptor ligands.

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