Drug General Information
Drug ID	D0P6VV
Former ID	DAP001100
Drug Name	Dezocine
Drug Type	Small molecular drug
Indication	Pain [ICD9: 338, 356.0, 356.8,780; ICD10:G64, G90.0, R52, G89]		Approved	[536361]
Therapeutic Class	Analgesics
Structure		Download 2D MOL 3D MOL
Formula	C16H23NO
Canonical SMILES	CC12CCCCCC(C1N)CC3=C2C=C(C=C3)O
InChIKey	VTMVHDZWSFQSQP-APHBMKBZSA-N
CAS Number	CAS 53648-55-8
PubChem Compound ID	6337211
PubChem Substance ID	56223384, 57366370, 134338347, 137005169, 225144371, 227587612, 242969056
SuperDrug ATC ID	N02AX03
SuperDrug CAS ID	cas=053648558
Target and Pathway
Target(s)	Kappa-type opioid receptor	Target Info	Antagonist	[536176]
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Opioid prodynorphin pathway
Reactome	Peptide ligand-binding receptors
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 536361	Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 536176	Pharmacological profiles of opioid ligands at kappa opioid receptors. BMC Pharmacol. 2006 Jan 25;6:3.

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