Drug Information

Drug General Information
Drug ID
D0Q6ZD
Former ID
DNC009924
Drug Name
[3H]A-804598
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540812]
Structure
Download
2D MOL

3D MOL
Formula
C19H17N5
InChI
InChI=1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1/i2T
InChIKey
PQYCRDPLPKGSME-MEVLSXKGSA-N
PubChem Compound ID
45481830
Target and Pathway
Target(s) P2X purinoceptor 7 Target Info Inhibitor [530221]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome The NLRP3 inflammasome
WikiPathways Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
References
Ref 540812(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5408).
Ref 530221Bioorg Med Chem. 2009 Jul 15;17(14):4861-5. Epub 2009 Jun 12.Purinergic P2X(7) receptor antagonists: Chemistry and fundamentals of biological screening.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.