Drug General Information
Drug ID	D0Q7UG
Former ID	DIB013763
Drug Name	Tipelukast
Synonyms	Asthma therapy, MediciNova; KCA-757; MN-001
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Phase 2	[525273]
Company	Kyorin Pharmaceutical Co Ltd
Structure		Download 2D MOL 3D MOL
Formula	C29H38O7S
Canonical SMILES	c1(c(ccc(c1CCC)SCCCOc1c(c(c(cc1)C(=O)C)OCCCC(=O)O)CCC)C<br />(=O)C)O
CAS Number	CAS 125961-82-2
PubChem Compound ID	9893228
Target and Pathway
Target(s)	Arachidonate 5-lipoxygenase	Target Info	Modulator
	Phosphodiesterase (PDE) 3	Target Info	Modulator
BioCyc Pathway	Aspirin-triggered lipoxin biosynthesis
	Resolvin D biosynthesis
	Leukotriene biosynthesis
	Lipoxin biosynthesis
	Aspirin triggered resolvin D biosynthesis
	Aspirin triggered resolvin E biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Serotonergic synapse
	Ovarian steroidogenesis
	Toxoplasmosis
NetPath Pathway	IL4 Signaling Pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Vitamin D Receptor Pathway
	Arachidonic acid metabolism
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 525273	ClinicalTrials.gov (NCT02503657) Safety and Tolerability Study in Subjects With Idiopathic Pulmonary Fibrosis (IPF).

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