Drug General Information
Drug ID	D0Q8MI
Former ID	DIB013200
Drug Name	Lintopride
Synonyms	SL-920075
Drug Type	Small molecular drug
Indication	Nausea [ICD10:R11]		Phase 2	[534100]
Company	Synthelabo
Structure		Download 2D MOL 3D MOL
Formula	C14H19ClN4O2
Canonical SMILES	c1(C(=O)NCC2=NCCN2CC)c(cc(c(c1)Cl)N)OC
CAS Number	CAS 107429-63-0
PubChem Compound ID	65900
Target and Pathway
Target(s)	5-hydroxytryptamine 4 receptor	Target Info	Modulator	[534100]
	5-HT 3 receptor	Target Info	Modulator	[534100]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT4 type receptor mediated signaling pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 4 and Serotonin
Reactome	Serotonin receptors
	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 534100	The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.
Ref 534100	The effects of lintopride, a 5HT-4 antagonist, on oesophageal motility. Aliment Pharmacol Ther. 1995 Oct;9(5):563-9.

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