Drug General Information
Drug ID	D0Q8TK
Former ID	DNC013539
Drug Name	1-(4-aminosulfonylphenyl)-2-(4-pyridyl)acetylene
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529156]
Structure		Download 2D MOL 3D MOL
Formula	C13H10N2O2S
Canonical SMILES	C1=CC(=CC=C1C#CC2=CC=NC=C2)S(=O)(=O)N
InChI	1S/C13H10N2O2S/c14-18(16,17)13-5-3-11(4-6-13)1-2-12-7-9-15-10-8-12/h3-10H,(H2,14,16,17)
InChIKey	WAURLAKEIUZSMJ-UHFFFAOYSA-N
PubChem Compound ID	44452472
Target and Pathway
Target(s)	Prostaglandin G/H synthase 1	Target Info	Inhibitor	[529156]
BioCyc Pathway	C20 prostanoid biosynthesis
KEGG Pathway	Arachidonic acid metabolism
	Metabolic pathways
	Platelet activation
	Serotonergic synapse
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
PANTHER Pathway	Inflammation mediated by chemokine and cytokine signaling pathway
PathWhiz Pathway	Arachidonic Acid Metabolism
WikiPathways	Prostaglandin Synthesis and Regulation
	Arachidonic acid metabolism
	Phase 1 - Functionalization of compounds
	Eicosanoid Synthesis
	Selenium Micronutrient Network
References
Ref 529156	Bioorg Med Chem. 2008 Feb 15;16(4):1948-56. Epub 2007 Nov 5.Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers.
Ref 529156	Bioorg Med Chem. 2008 Feb 15;16(4):1948-56. Epub 2007 Nov 5.Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.