Drug General Information
Drug ID
D0R3OR
Former ID
DIB016655
Drug Name
SR-27950
Synonyms
SR-27899
Indication Eating disorder [ICD9: 278, 307.5, 401, 428.0; ICD10:E66, F50, I10-I16, I50] Terminated [544831]
Company
Sanofi
Structure
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2D MOL

3D MOL

Canonical SMILES
n1(c(C(=O)N[C@H]2N=C(c3c(NC2=O)cccc3)c2ccccc2)cc2c1cccc<br />2)CC(=O)O
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Modulator [543960]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 544831Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001260)
Ref 543960(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 76).

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