Drug Information

Drug General Information
Drug ID
D0R6FJ
Former ID
DNC011502
Drug Name
NORHARMANE
Drug Type
Small molecular drug
Indication Discovery agent Investigative [543001]
Structure
Download
2D MOL

3D MOL
Formula
C11H8N2
InChI
InChI=1S/C11H8N2/c1-2-4-10-8(3-1)9-5-6-12-7-11(9)13-10/h1-7,13H
InChIKey
AIFRHYZBTHREPW-UHFFFAOYSA-N
PubChem Compound ID
64961
PubChem Substance ID
122166, 646046, 855536, 3134108, 5536206, 7980024, 8189408, 10321411, 10515297, 11364026, 11366588, 11369150, 11371642, 11375670, 11377312, 11448734, 11484172, 11488404, 11490557, 11493729, 11494946, 11537690, 12015776, 14843142, 22388129, 24897776, 26679360, 26746906, 29204446, 30134734, 32469833, 37423398, 43121816, 47217266, 47811249, 48259727, 48414245, 49748324, 49748325, 49857602, 50100962, 50103899, 50734380, 53787843, 56422412, 57315208, 81093147, 85088300, 85315305, 85789440
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533363]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533363]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 543001(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8222).
Ref 533363J Med Chem. 1988 Sep;31(9):1854-61.Synthesis of novel 3-substituted beta-carbolines as benzodiazepine receptor ligands: probing the benzodiazepine receptor pharmacophore.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.