Drug Information

Drug General Information
Drug ID
D0R7FI
Former ID
DNC007497
Drug Name
4-phenyl-1-(1-phenylpropan-2-yl)piperidin-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528785]
Structure
Download
2D MOL

3D MOL
Formula
C20H25NO
Canonical SMILES
CC(CC1=CC=CC=C1)N2CCC(CC2)(C3=CC=CC=C3)O
InChI
1S/C20H25NO/c1-17(16-18-8-4-2-5-9-18)21-14-12-20(22,13-15-21)19-10-6-3-7-11-19/h2-11,17,22H,12-16H2,1H3
InChIKey
DBTIAPBSTRWDLH-UHFFFAOYSA-N
PubChem Compound ID
44426805
Target and Pathway
Target(s) Nociceptin receptor Target Info Inhibitor [528785]
KEGG Pathway Neuroactive ligand-receptor interaction
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 528785Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.
Ref 528785Bioorg Med Chem Lett. 2007 Jun 1;17(11):3023-7. Epub 2007 Mar 23.Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.