TTD | Drug: D0R7VT

Drug General Information
Drug ID	D0R7VT
Former ID	DNC005950
Drug Name	4-(1H-indol-1-ylsulfonyl)benzenamine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527760]
Structure		Download 2D MOL 3D MOL
Formula	C14H12N2O2S
Canonical SMILES	C1=CC=C2C(=C1)C=CN2S(=O)(=O)C3=CC=C(C=C3)N
InChI	1S/C14H12N2O2S/c15-12-5-7-13(8-6-12)19(17,18)16-10-9-11-3-1-2-4-14(11)16/h1-10H,15H2
InChIKey	FLNRELDLHZADER-UHFFFAOYSA-N
PubChem Compound ID	44263491
Target and Pathway
Target(s)	5-hydroxytryptamine 6 receptor	Target Info	Inhibitor	[527760]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PathWhiz Pathway	Excitatory Neural Signalling Through 5-HTR 6 and Serotonin
Reactome	Serotonin receptors
Reactome	G alpha (s) signalling events
WikiPathways	Serotonin Receptor 4/6/7 and NR3C Signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527760	Bioorg Med Chem Lett. 2005 Dec 1;15(23):5298-302. Epub 2005 Sep 23.Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.
Ref 527760	Bioorg Med Chem Lett. 2005 Dec 1;15(23):5298-302. Epub 2005 Sep 23.Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors.

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Drug Information