Drug Information

Drug General Information
Drug ID
D0R8GW
Former ID
DIB018741
Drug Name
AC-7954
Synonyms
AC7954; AC 7954
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539367]
Structure
Download
2D MOL
Formula
C19H20ClNO2
InChI
InChI=1S/C19H20ClNO2/c1-21(2)12-11-19(15-7-9-16(20)10-8-15)13-14-5-3-4-6-17(14)18(22)23-19/h3-10H,11-13H2,1-2H3
InChIKey
HIVBATDUVFEJFZ-UHFFFAOYSA-N
PubChem Compound ID
9797568
PubChem Substance ID
14753143, 24107201, 29217713, 44833576, 50111724, 57373357, 76106023, 85208935, 85788707, 103465081, 104050205, 135649883, 139059392, 143109521, 230688288, 246820731
Target and Pathway
Target(s) Urotensin II receptor Target Info Agonist [527493]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539367(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2151).
Ref 527493Isochromanone-based urotensin-II receptor agonists. Bioorg Med Chem. 2005 Apr 15;13(8):3057-68.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.