Drug Information

Drug General Information
Drug ID
D0RI4S
Former ID
DNC007576
Drug Name
2-benzyl-2H-pyrazolo[3,4-c]quinolin-4(5H)-one
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528969]
Structure
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2D MOL

3D MOL
Formula
C17H13N3O
Canonical SMILES
C1=CC=C(C=C1)CN2C=C3C4=CC=CC=C4NC(=O)C3=N2
InChI
1S/C17H13N3O/c21-17-16-14(13-8-4-5-9-15(13)18-17)11-20(19-16)10-12-6-2-1-3-7-12/h1-9,11H,10H2,(H,18,21)
InChIKey
XJRYZVBNFXKWFF-UHFFFAOYSA-N
PubChem Compound ID
10636110
Target and Pathway
Target(s) Adenosine A3 receptor Target Info Inhibitor [528969]
Reactome Adenosine P1 receptors
G alpha (i) signalling events
WikiPathways Nucleotide GPCRs
GPCRs, Class A Rhodopsin-like
GPCRs, Other
References
Ref 528969J Med Chem. 2007 Aug 23;50(17):4061-74. Epub 2007 Aug 1.New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.
Ref 528969J Med Chem. 2007 Aug 23;50(17):4061-74. Epub 2007 Aug 1.New 2-arylpyrazolo[3,4-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. Synthesis, pharmacological evaluation, and ligand-receptor modeling studies.

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