Drug General Information
Drug ID	D0S0GM
Former ID	DIB006484
Drug Name	ADX-10061
Synonyms	CEE-310; NNC-687; NO-687; CEE-03-310; NNC-01-0687; NNC-01-687
Indication	Psychotic disorders [ICD9: 290-299; ICD10:F20-F29]		Discontinued in Phase 2	[544910]
Company	Addex Pharmaceuticals; Novo Nordisk A/S
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1([N+](=O)[O-])cc2c([C@@H](c3c4OCCc4ccc3)CN(CC2)C)cc1O
CAS Number	CAS 128022-68-4
Target and Pathway
Target(s)	Dopamine D1 receptor	Target Info	Antagonist	[544911]
KEGG Pathway	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Dopaminergic synapse
	Parkinson's disease
	Cocaine addiction
	Amphetamine addiction
	Morphine addiction
	Alcoholism
PANTHER Pathway	Dopamine receptor mediated signaling pathway
PathWhiz Pathway	Dopamine Activation of Neurological Reward System
Reactome	Dopamine receptors
	G alpha (s) signalling events
WikiPathways	Hypothetical Network for Drug Addiction
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Genes and (Common) Pathways Underlying Drug Addiction
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544910	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001476)
Ref 544911	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001476)

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