TTD | Drug: D0S0OV

Drug General Information
Drug ID	D0S0OV
Former ID	DNC004513
Drug Name	1-(7-Methoxy-2-phenyl-chroman-4-yl)-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527222]
Structure		Download 2D MOL 3D MOL
Formula	C19H18N2O2
Canonical SMILES	COC1=CC2=C(C=C1)C(CC(O2)C3=CC=CC=C3)N4C=CN=C4
InChI	1S/C19H18N2O2/c1-22-15-7-8-16-17(21-10-9-20-13-21)12-18(23-19(16)11-15)14-5-3-2-4-6-14/h2-11,13,17-18H,12H2,1H3
InChIKey	JEQHTTKNYWNYDK-UHFFFAOYSA-N
PubChem Compound ID	10267149
Target and Pathway
Target(s)	Cytochrome P450 19	Target Info	Inhibitor	[527222]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Estradiol biosynthesis II
	Estradiol biosynthesis I
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
	Ovarian steroidogenesis
NetPath Pathway	FSH Signaling Pathway
PANTHER Pathway	Androgen/estrogene/progesterone biosynthesis
PathWhiz Pathway	Androgen and Estrogen Metabolism
Reactome	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Tryptophan metabolism
	Oxidation by Cytochrome P450
	Ovarian Infertility Genes
	Metabolism of steroid hormones and vitamin D
	FSH signaling pathway
	Integrated Breast Cancer Pathway
	Phase 1 - Functionalization of compounds
References
Ref 527222	Bioorg Med Chem Lett. 2004 Oct 18;14(20):5215-8.Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors.
Ref 527222	Bioorg Med Chem Lett. 2004 Oct 18;14(20):5215-8.Synthesis and evaluation of 4-triazolylflavans as new aromatase inhibitors.

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Drug Information