TTD | Drug: D0S8MS

Drug General Information
Drug ID	D0S8MS
Former ID	DIB020611
Drug Name	ONO-9910539
Synonyms	ON9
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533273]
Structure		Download 2D MOL
Formula	C32H37NO8
InChI	InChI=1S/C32H37NO8/c1-19(34)30-27(39-2)14-24(15-28(30)40-3)31(37)25(13-20-11-21-7-5-6-8-22(21)12-20)17-33-16-23(9-10-29(35)36)26(18-33)32(38)41-4/h5-8,14-16,18,20,25,31,37H,9-13,17H2,1-4H3,(H,35,36)/t25-,31+/m0/s1
InChIKey	URHZQBASTULQKJ-VVFBEHOQSA-N
PubChem Compound ID	91799237
PubChem Substance ID	251963607, 252166791
Target and Pathway
Target(s)	Lysophosphatidic acid receptor Edg-2	Target Info	Antagonist	[533273]
KEGG Pathway	Rap1 signaling pathway
	Neuroactive ligand-receptor interaction
	PI3K-Akt signaling pathway
	Gap junction
	Pathways in cancer
NetPath Pathway	TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database	LPA receptor mediated events
Reactome	G alpha (q) signalling events
	G alpha (i) signalling events
	Lysosphingolipid and LPA receptors
WikiPathways	Myometrial Relaxation and Contraction Pathways
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 533273	Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.
Ref 533273	Crystal Structure of Antagonist Bound Human Lysophosphatidic Acid Receptor 1. Cell. 2015 Jun 18;161(7):1633-43.

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Drug Information