Drug General Information
Drug ID	D0S9YE
Former ID	DNC012604
Drug Name	(beta-CCE)9H-beta-Carboline-3-carboxylic acid
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[526738]
Structure		Download 2D MOL 3D MOL
Formula	C12H8N2O2
Canonical SMILES	C1=CC=C2C(=C1)C3=CC(=NC=C3N2)C(=O)O
InChI	1S/C12H8N2O2/c15-12(16)10-5-8-7-3-1-2-4-9(7)14-11(8)6-13-10/h1-6,14H,(H,15,16)
InChIKey	ARLVFKCLBYUINL-UHFFFAOYSA-N
PubChem Compound ID	173262
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[526738]
	Gamma-aminobutyric acid receptor subunit gamma-2	Target Info	Inhibitor	[526738]
	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[526738]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 526738	J Med Chem. 1992 Jun 12;35(12):2214-20.Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.
Ref 526738	J Med Chem. 1992 Jun 12;35(12):2214-20.Benzodiazepine receptor affinity and interaction of some N-(indol-3-ylglyoxylyl)amine derivatives.

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